Organisers

Daniel Berrar, University of Ulster, Coleraine
Werner Dubitzky, University of Ulster, Coleraine

Introduction

As natural phenomena are being probed and mapped in ever-greater detail, scientists in genomics and proteomics are facing an exponentially growing volume of increasingly complex-structured data, information, and knowledge. This is particularly true for information related to genomic function, ie molecular information represented by DNA and how this information affects the function of different species under different conditions. A fundamental challenge of functional genomics is to explore, analyze and interpret this information effectively and efficiently. To address this challenge, traditional statistical methods are being complemented by methods from data mining, machine learning and artificial intelligence, and support technologies such as high-performance and computing. The sheer volume of data generated by high-throughput technologies in genomics and proteomics like DNA microarray gene expression analysis and mass spectrometry data, present unprecedented new challenges to the data analyst.

This workshop will discuss state of the art analytical methods to address key analysis tasks that data from functional genomics involve. A particular emphasis of this workshop is placed on functional genomics approaches that are driven by systems biology, involving the interaction of genomic information with information at different levels of biological organization. Hence, studies that integrate genomics (eg DNA microarrays) and proteomics (eg mass spectrometry) techniques to elucidate complex biological phenomena such as cancer are of particular interest. Another key consideration resulting from the system view relates to the study of system dynamics arising from genomic information and its processing in the cell.

This workshop is intended for academic researchers and industrial practitioners who wish to understand the state of the art of the presented methods and identify the areas in which gaps in our knowledge demand further research and development. To this end, a key aim of the workshop is to demonstrate the practical application of the methods in the context of real questions and problems encountered in research and development. With the attendance of high-caliber researchers and industrial practitioners, we expect that the workshop will facilitate new partnerships, help identify opportunities for further research, development and applications, and defined strategies to advance the field.

Workshop Themes - Focusing on actual questions, problems and applications arising in research, development and real-world applications, the workshop will focus on two major themes:
(1) State of the art and challenges in analyzing high-throughput data in functional genomics and proteomics.
This theme addresses the state of the art of analytical methods from data mining, statistics, machine learning, and artificial intelligence for the analysis of high-throughput data such as DNA microarrays (genomics) and mass spectrometry data (proteomics). The key challenges and limitations of current methods are discussed. The requirements for next generation methods will be identified.
(2) State of the art and challenges in integrative systems biology.
This theme addresses the issues related to the integration of heterogeneous data arising from genomics and proteomics experiments in order to support the systemic analysis (interaction of genomic and proteomics information with other elements and system dynamics).

Venue

The meeting will be held at the University of Ulster Coleraine Campus.

Registration

Registration is now closed.

Draft Programme

Tuesday 8th May
08:30-08:45 Registration
08:45-09:00 Welcome and Introduction
09:00-09:30 Novel Data Mining Approaches for Integrative Systems Biology - Dr. Daniel Berrar
09:45-10:30 Title to be confirmed - Prof. Dr. Tony Bjourson
10:30-11:15 Title to be confirmed - Prof. Dr. Martin Stetter
11:15-11:30 Coffee Break
11:30-12:15 Title to be confirmed - Prof. Dr. Jean-Michel Claverie
12:15-13:30 Lunch
13:30-14:15 Integrating Gene Expression and Transcription Factor Binding Site Data Sets - Prof. Dr. Des Higgins
14:15-15:00 Title to be confirmed - Prof. Dr. Alvis Brazma
15:00-15:15 Coffee Break
15:15-16:00 Title to be confirmed - Prof. Dr. Mark Girolami
16:00-16:45 Title to be confirmed - Prof. Dr. Joaquin Dopazo
16:45-17:45 Summary and Open Discussion
17:45-20:00 Reception

Wednesday 9th May
08:45-09:30 Title to be confirmed
09:30-10:15 Title to be confirmed
10:15-11:00 Networks in Cell Biology - Dr. Carlos Rodrigues-Caso
11:00-11:15 Coffee Break
11:15-12:00 Title to be confirmed - Prof. Dr. Rui Brito
12:00-13:30 Lunch
13:30-14:15 Title to be confirmed - Dr. Markus Ringnér
14:15-15:00 Title to be confirmed
15:00-15:45 Title to be confirmed
15:45-16:00 Coffee Break
16:00-17:30 Summary and Discussion
17:30-20:00 Reception

Speakers

Markus Ringer, Lund University
Joaquin Dopazo, CIPF, Valencia
Martin Stetter, Technical University of Munich
Mark Girolami, University of Glasgow
Alvis Brazma, EBI, Cambridge
Des Higgins, University College Dublin
Carlos Rodriguez-Caso, Barcelona
Jean-Michel Claverie, CNRS, Marseille
Tony Bjourson, University of Ulster
Michael Berthold, University of Konstanz
Rui Brito, University of Coimbra, Portugal
Geoff McMullan, University of Ulster
Jean-Daniel Zucker, Université Paris 6