Proteomics

 

 

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[Analysis of phenotypic changes resulting from mutagenesis and gene disruption]
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[Mutagenesis and phenotype]
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[Antisense oligonucleotides and ribozymes as gene knockdown reagents]

Analysis of phenotypic changes resulting from mutagenesis and gene disruption

Mutation and gene disruption are powerful tools for investigating gene function and for identifying novel genes without prior knowledge of homology in other systems. Screening for phenotypes of interest leads to discovery of new genes, some of the mutations becoming models for human genetic diseases. The programme includes groups working on diverse model organisms including mouse, plants, yeast and bacteria.

> Mutagenesis and phenotype
> Antisense oligonucleotides and ribozymes as gene knockdown reagents

Contacts within the programme
John Armstrong
Rudi Balling

Steve Brown
Charles Buys
Rosane Curtis
Victor De Lorenzo
Jean-Luc Desseyn
J Richard Dickinson
Joachim Engels
Ilana Harav

Juha Kere
Thomas Martin
Thomas Meyer
Ross Miller
Ronald Plasterk
Annemarie Poustka
Bruna Scaggiante
Ed Southern
Carmen Sotelo
Leonid Titov
Daniela Toniolo
Eugen Uhlmann
Antonio Vidal-Puig
Matthew Wood