Protein Array References
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Selected literature dealing with aspects of design and applications of protein arrays
(URLs for abstracts are provided).

indicates an addition in the most recent page update (April 2004)

Original Papers

Reviews

Original papers

2004

Angenendt P, Nyarsik L, Szaflarski W, Glokler J, Nierhaus KH, Lehrach H, Cahill DJ, Lueking A. (2004) Cell-Free Protein Expression and Functional Assay in Nanowell Chip Format. Anal Chem. 76:1844-1849

Bock C, Coleman M, Collins B, Davis J, Foulds G, Gold L, Greef C, Heil J, Heilig JS, Hicke B, Hurst MN, Husar GM, Miller D, Ostroff R, Petach H, Schneider D, Vant-Hull B, Waugh S, Weiss A, Wilcox SK, Zichi D (2004) Photoaptamer arrays applied to multiplexed proteomic analysis. Proteomics 4:609-18

Copeland S, Siddiqui J, Remick D (2004) Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
J Immunol Methods 284:99-106.

Delehanty JB (2004) Printing functional protein microarrays using piezoelectric capillaries. Methods Mol Biol. 278:135-44

Feng Y, Ke X, Ma R, Chen Y, Hu G, Liu F (2204) Parallel detection of autoantibodies with microarrays in rheumatoid diseases. Clin. Chem. 50:416-22.

Gilbert I, Schiffmann S, Rubenwolf S, Jensen K, Mai T, Albrecht C, Lankenau A, Beste G, Blank K, Gaub HE, Clausen-Schaumann H (2004) Double chip protein arrays using recombinant single-chain Fv antibody fragments. Proteomics 4:

Huang R, Lin Y, Shi Q, Flowers L, Ramachandran S, Horowitz IR, Parthasarathy S, Huang RP (2004) Enhanced protein profiling arrays with ELISA-based amplification for high-throughput molecular changes of tumor patients' plasma.
Clin Cancer Res. 10:598-609.

Jung GY, Stephanopoulos G (2004) A functional protein chip for pathway optimization and in vitro metabolic engineering. Science 304:428-31

Kiyonaka S, Sada K, Yoshimura I, Shinkai S, Kato N, Hamachi I (2004) Semi-wet peptide/protein array using supramolecular hydrogel. Nature Materials 3:58-64.

Knecht BG, Strasser A, Dietrich R, Martlbauer E, Niessner R, Weller MG (2004) Automated microarray system for the simultaneous detection of antibiotics in milk.
Anal Chem. 76:646-54.

Lue RY, Chen GY, Zhu Q, Lesaicherre ML, Yao SQ (2004) Site-specific immobilization of biotinylated proteins for protein microarray analysis.
Methods Mol Biol. 278:85-100.

Marquette CA, Blum LJ (2004) Direct immobilization in poly(dimethylsiloxane) for DNA, protein and enzyme fluidic biochips. Analytica Chimica Acta 506:127-132

Morgan E, Varro R, Sepulveda H, Ember JA, Apgar J, Wilson J, Lowe L, Chen R, Shivraj L, Agadir A, Campos R, Ernst D, Gaur A (2004) Cytometric bead array: a multiplexed assay platform with applications in various areas of biology.
Clin Immunol. 110:252-66

Rychlewski L, Kschischo M, Dong L, Schutkowski M, Reimer U (2004) Target specificity analysis of the Abl kinase using peptide microarray data.
J Mol Biol. 336:307-11.

Sapsford KE, Shubin YS, Delehanty JB, Golden JP, Taitt CR, Shriver-Lake LC, Ligler FS (2004) Fluorescence-based array biosensors for detection of biohazards.
J Appl Microbiol. 96:47-58.

Schroeder CM, Ott H, Merk HF, Baron JM (2004) Aachen atopy array. A novel allergen chip technique for the analysis of serum IgE antibodies to recombinant latex allergens. J Allergy Clin Immunol 113:S329

Song JM, Vo-Dinh T (2004) Miniature biochip system for detection of Escherichia coli O157:H7 based on antibody-immobilized capillary reactors and enzyme-linked immunosorbent assay. Analytica Chimica Acta 507:115-121

Turtinen LW, Prall DN, Bremer LA, Nauss RE, Hartsel SC (2004) Antibody array-generated profiles of cytokine release from THP-1 leukemic monocytes exposed to different amphotericin B formulations. Antimicrob Agents Chemother. 48:396-403.

Varnum SM, Woodbury RL, Zangar RC (2004) A protein microarray ELISA for screening biological fluids. Methods Mol Biol. 278:161-72

Wang Y (2004) Immunostaining with dissociable antibody microarrays. Proteomics. 4:20-6.

Zha H, Raffeld M, Charboneau L, Pittaluga S, Kwak LW, Petricoin E 3rd, Liotta LA, Jaffe ES (2004) Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray.
Lab Invest. 84:235-44

2003

Angenendt P, Glokler J, Konthur Z, Lehrach H, Cahill DJ (2003) 3D protein microarrays: performing multiplex immunoassays on a single chip.
Anal Chem.75:4368-72

Angenendt P, Glokler J, Sobek J, Lehrach H, Cahill DJ (2003) Next generation of protein microarray support materials: evaluation for protein and antibody microarray applications. J Chromatogr A. 1009:97-104.

Arntz Y., Seelig J.D., Lang H.P., Zhang J., Hunziker P., Ramseyer J.P., Meyer E., Hegner M., Gerber C. (2003) Label-free protein assay based on a nanomechanical cantilever array. Nanotechnology 14:86-90

Barry R, Diggle T, Terrett J, Soloviev M (2003) Competitive assay formats for high-throughput affinity arrays. J Biomol Screen. 8:257-63

Blank K, Mai T, Gilbert I, Schiffmann S, Rankl J, Zivin R, Tackney C, Nicolaus T, Spinnler K, Oesterhelt F, Benoit M, Clausen-Schaumann H, Gaub HE (2003) A force-based protein biochip. Proc Natl Acad Sci USA 100:11356-60

Bouwman K, Qiu J, Zhou H, Schotanus M, Mangold LA, Vogt R, Erlandson E, Trenkle J, Partin AW, Misek D, Omenn GS, Haab BB, Hanash S. (2003) Microarrays of tumor cell derived proteins uncover a distinct pattern of prostate cancer serum immunoreactivity. Proteomics 3:2200-7

Chen GY, Uttamchandani M, Zhu Q, Wang G, Yao SQ (2003) Developing a Strategy for Activity-Based Detection of Enzymes in a Protein Microarray.
Chembiochem 4:336-339

Delehanty JB, Ligler FS (2003) Method for printing functional protein microarrays.
Biotechniques 34:380-5

Du W, Xu Z, Ma X, Song L, Schneider EM (2003) Biochip as a potential platform of serological interferon alpha2b antibody assay. J Biotechnol. 106:87-100

Gosalia DN, Diamond SL (2003) Printing chemical libraries on microarrays for fluid phase nanoliter reactions. Proc Natl Acad Sci U S A 100:8721-6

Kawahashi Y, Doi N, Takashima H, Tsuda C, Oishi Y, Oyama R, Yonezawa M, Miyamoto-Sato E, Yanagawa H (2003) In vitro protein microarrays for detecting protein-protein interactions: application of a new method for fluorescence labeling of proteins. Proteomics 3:1236-43

Kersten B, Feilner T, Kramer A, Wehrmeyer S, Possling A, Witt I, Zanor MI, Stracke R, Lueking A, Kreutzberger J, Lehrach H, Cahilll DJ (2003) Generation of Arabidopsis protein chips for antibody and serum screening. Plant Mol Biol. 52:999-1010

Kim J, Park H, Jung D, Kim S (2003) Protein immobilization on plasma-polymerized ethylenediamine-coated glass slides. Anal Biochem 313:41-5

Kojima K, Hiratsuka A, Suzuki H, Yano K, Ikebukuro K, Karube I (2003) Electrochemical protein chip with arrayed immunosensors with antibodies immobilized in a plasma-polymerized film. Anal Chem 75:1116-22

Koopmann JO, Blackburn J (2003) High affinity capture surface for matrix-assisted laser desorption/ionisation compatible protein microarrays. Rapid Commun Mass Spectrom. 17:455-62.

Kusnezow W, Hoheisel JD (2003) Solid supports for microarray immunoassays.
J Mol Recognit. 16:165-76.

Kusnezow W, Jacob A, Walijew A, Diehl F, Hoheisel JD (2003) Antibody microarrays: An evaluation of production parameters. Proteomics 3:254-64

Lee K-N., Shin D-S., Lee Y-S., Kim Y-K. (2003) Protein patterning by virtual mask photolithography using a micromirror array. J Micromechanics Microeng 13:18-25

Lee Y, Lee EK, Cho YW, Matsui T, Kang IC, Kim TS, Han MH (2003) ProteoChip: a highly sensitive protein microarray prepared by a novel method of protein immobilization for application of protein-protein interaction studies.
Proteomics 3:2289-304

Lueking A, Possling A, Huber O, Beveridge A, Horn M, Eickhoff H, Schuchardt J, Lehrach H, Cahill DJ (2003) A non-redundant human protein chip for antibody screening and serum profiling. Mol Cell Proteomics. Sep 29

Levit-Binnun N, Lindner AB, Zik O, Eshhar Z, Moses E (2003) Quantitative detection of protein arrays. Anal Chem 75:1436-41

Ligler FS, Taitt CR, Shriver-Lake LC, Sapsford KE, Shubin Y, Golden JP (2003) Array biosensor for detection of toxins. Anal Bioanal Chem. 2003 377:469-77

Lin Y, Huang R, Cao X, Wang SM, Shi Q, Huang RP (2003) Detection of multiple cytokines by protein arrays from cell lysate and tissue lysate.
Clin Chem Lab Med 41:139-45

Lin Y, Huang R, Chen LP, Lisoukov H, Lu ZH, Li S, Wang CC, Huang RP (2003) Profiling of cytokine expression by biotin-labeled-based protein arrays.
Proteomics 3:1750-7

Li Y, Nath N, Reichert WM (2003) Parallel comparison of sandwich and direct label assay protocols on cytokine detection protein arrays. Anal Chem. 75:5274-81

Marquette CA, Thomas D, Degiuli A, Blum LJ. (2003) Design of luminescent biochips based on enzyme, antibody, or DNA composite layers.
Anal Bioanal Chem. 377:922-8

Michaud GA, Salcius M, Zhou F, Bangham R, Bonin J, Guo H, Snyder M, Predki PF, Schweitzer BI (2003) Analyzing antibody specificity with whole proteome microarrays.
Nat Biotechnol. 21:1509-12

Miller JC, Zhou H, Kwekel J, Cavallo R, Burke J, Butler EB, Teh BS, Haab BB (2003) Antibody microarray profiling of human prostate cancer sera: Antibody screening and identification of potential biomarkers. Proteomics 3:56-63

Moreno-Bondi MC, Alarie JP, Vo-Dinh T (2003) Multi-analyte analysis system using an antibody-based biochip. Anal Bioanal Chem 375:120-124

Morozov VN, Morozova TY, Johnson KL, Naylor S. (2003) Parallel determination of multiple protein metabolite interactions using cell extract, protein microarrays and mass spectrometric detection. Rapid Commun Mass Spectrom. 17:2430-8

Naffin JL, Han Y, Olivos HJ, Reddy MM, Sun T, Kodadek T. (2003) Immobilized peptides as high-affinity capture agents for self-associating proteins.
Chem Biol. 10:251-9

Nam JM, Thaxton CS, Mirkin CA (2003) Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins. Science 301:1884-6

Nath N, Chilkoti A (2003) Fabrication of a reversible protein array directly from cell lysate using a stimuli-responsive polypeptide. Anal Chem. 75:709-15

Neuman de Vegvar HE, Amara RR, Steinman L, Utz PJ, Robinson HL, Robinson WH (2003) Microarray profiling of antibody responses against simian-human immunodeficiency virus: postchallenge convergence of reactivities independent of host histocompatibility type and vaccine regimen. J Virol. 7720:11125-38

Nettikadan SR, Johnson JC, Mosher C, Henderson E. (2003) Virus particle detection by solid phase immunocapture and atomic force microscopy.
Biochem Biophys Res Commun. 311:540-5

Nielsen UB, Cardone MH, Sinskey AJ, MacBeath G, Sorger PK (2003) Profiling receptor tyrosine kinase activation by using Ab microarrays.
Proc Natl Acad Sci USA 100:9330-5

Nishizuka S, Charboneau L, Young L, Major S, Reinhold WC, Waltham M, Kouros-Mehr H, Bussey KJ, Lee JK, Espina V, Munson PJ, Petricoin E 3rd, Liotta LA, Weinstein JN. (2003) Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays. Proc Natl Acad Sci USA 100:14229-34

Nord O, Uhlen M, Nygren PA (2003) Microbead display of proteins by cell-free expression of anchored DNA. J Biotechnol. 106:1-13

Oleinikov AV, Gray MD, Zhao J, Montgomery DD, Ghindilis AL, Dill K (2003) Self-Assembling Protein Arrays Using Electronic Semiconductor Microchips and in Vitro Translation. J. Proteome Research, 2, 313 -319.

Ouyang Z, Takats Z, Blake TA, Gologan B, Guymon AJ, Wiseman JM, Oliver JC, Davisson VJ, Cooks RG (2003) Preparing protein microarrays by soft-landing of mass-selected ions. Science 301:1351-4.

Pavlickova P, Knappik A, Kambhampati D, Ortigao F, Hug H (2003) Microarray of recombinant antibodies using a streptavidin sensor surface self-assembled onto a gold layer. Biotechniques 34:124-30

Peluso P, Wilson DS, Do D, Tran H, Venkatasubbaiah M, Quincy D, Heidecker B, Poindexter K, Tolani N, Phelan M, Witte K, Jung LS, Wagner P, Nock S (2003) Optimizing antibody immobilization strategies for the construction of protein microarrays. Anal Biochem 312:113-24

Robinson WH, Fontoura P, Lee BJ, de Vegvar HE, Tom J, Pedotti R, DiGennaro CD, Mitchell DJ, Fong D, Ho PP, Ruiz PJ, Maverakis E, Stevens DB, Bernard CC, Martin R, Kuchroo VK, van Noort JM, Genain CP, Amor S, Olsson T, Utz PJ, Garren H, Steinman L. (2003) Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis. Nat Biotechnol. 21:1033-9

Rubina AY, Dementieva EI, Stomakhin AA, Darii EL, Pan'kov SV, Barsky VE, Ivanov SM, Konovalova EV, Mirzabekov AD (2003) Hydrogel-based protein microchips: manufacturing, properties, and applications. Biotechniques 34:1008-1022.

Rupcich N, Goldstein A, Brennan JD (2003) Optimization of Sol-Gel Formulations and Surface Treatments for the Development of Pin-Printed Protein Microarrays. Chem. Mater., 15, 1803 -1811

Scrivener E, Barry R, Platt A, Calvert R, Masih G, Hextall P, Soloviev M, Terrett J (2003) Peptidomics: A new approach to affinity protein microarrays.
Proteomics 3:122-8

Smith D, Collins BD, Heil J, Koch TH (2003) Sensitivity and specificity of photoaptamer probes. Mol Cell Proteomics 2:11-8

Stevens PW, Wang CH, Kelso DM (2003) Immobilized particle arrays: coalescence of planar- and suspension-array technologies. Anal Chem 75:1141-6

Stich N, van Steen G, Schalkhammer T (2003) Design and peptide-based validation of phage display antibodies for proteomic biochips. Comb Chem High Throughput Screen 6:67-78

Tannapfel A, Anhalt K, Hausermann P, Sommerer F, Benicke M, Uhlmann D, Witzigmann H, Hauss J, Wittekind C. (2003) Identification of novel proteins associated with hepatocellular carcinomas using protein microarrays.
J Pathol. 201:238-49

Wiese R (2003) Analysis of several fluorescent detector molecules for protein microarray use. Luminescence 2003 18:25-30

Yan H, Park SH, Finkelstein G, Reif JH, LaBean TH (2003) DNA-Templated Self-Assembly of Protein Arrays and Highly Conductive Nanowires. Science 301:1882-4

Yi SJ, Yuk JS, Jung SH, Zhavnerko GK, Kim YM, Ha KS (2003) Investigation of selective protein immobilization on charged protein array by wavelength interrogation-based SPR sensor. Mol Cells 15:333-40

Yuza Y, Agawa M, Matsuzaki M, Yamada H, Urashima M (2003) Gene and protein expression profiling during differentiation of neuroblastoma cells triggered by 13-cis retinoic acid. J Pediatr Hematol Oncol. 25:715-20

Zhang CX, Liu HP, Tang ZM, He NY, Lu ZH (2003) Cell detection based on protein array using modified glass slides. Electrophoresis 24:3279-83

2002

Angenendt P, Glokler J, Murphy D, Lehrach H, Cahill DJ. (2002) Toward optimized antibody microarrays: a comparison of current microarray support materials.
Anal Biochem 309:253-60

Askari MD, Miller GH, Vo-Dinh T (2002) Simultaneous detection of the tumor suppressor FHIT gene and protein using the multi-functional biochip.
Cancer Detect Prev 26:331-42

Avseenko NV, Morozova TY, Ataullakhanov FI, Morozov VN (2002)
Immunoassay with multicomponent protein microarrays fabricated by electrospray deposition Anal Chem 74:927-33

Bacarese-Hamilton T, Bistoni F, Crisanti A. (2002) Protein microarrays: from serodiagnosis to whole proteome scale analysis of the immune response against pathogenic microorganisms. Biotechniques Dec;Suppl:24-29

Bacarese-Hamilton T, Mezzasoma L, Ingham C, Ardizzoni A, Rossi R, Bistoni F, Crisanti A (2002) Detection of allergen-specific IgE on microarrays by use of signal amplification techniques Clin Chem 48:1367-70

Barsky VE, Kolchinsky AM, Lysov YP, Mirzabekov AD (2002) Biological Microchips with Hydrogel-Immobilized Nucleic Acids, Proteins, and Other Compounds: Properties and Applications in Genomics. Molecular Biology 36:437-455

Delehanty JB, Ligler FS. (2002) A microarray immunoassay for simultaneous detection of proteins and bacteria. Anal Chem 74:5681-7

Espejo A, Cote J, Bednarek A, Richard S, Bedford MT (2002) A protein-domain microarray identifies novel protein-protein interactions Biochem J 2002 Jul 23Pt

Fang Y, Frutos AG, Lahiri J (2002) G-protein-coupled receptor microarrays. Chembiochem 3:987-91

Fang Y, Frutos AG, Lahiri J (2002) Membrane protein microarrays
J Am Chem Soc 2002 124:2394-5

Fang Y, Frutos AG, Webb B, Hong Y, Ferrie A, Lai F, Lahiri J (2002) Membrane biochips. Biotechniques Dec;Suppl:62-5

Fredriksson S, Gullberg M, Jarvius J, Olsson C, Pietras K, Gustafsdottir SM,
Ostman A, Landegren U. (2002) Protein detection using proximity-dependent DNA ligation assays. Nature Biotechnol 20:473-477

Hiller R, Laffer S, Harwanegg C, Huber M, Schmidt WM, Twardosz A, Barletta B,
Becker WM, Blaser K, Breiteneder H, Chapman M, Crameri R, Duchene M, Ferreira F,
Fiebig H, Hoffmann-Sommergruber K, King TP, Kleber-Janke T, Kurup VP, Lehrer SB,
Lidholm J, Muller U, Pini C, Reese G, Scheiner O, Scheynius A, Shen HD, Spitzauer S,
Suck R, Swoboda I, Thomas W, Tinghino R, Van Hage-Hamsten M, Virtanen T, Kraft D, Muller MW, Valenta R (2002)
Microarrayed allergen molecules: diagnostic gatekeepers for allergy treatment
FASEB J 16:414-6

Hodneland CD, Lee YS, Min DH, Mrksich M. (2002) Supramolecular Chemistry And Self-assembly Special Feature: Selective immobilization of proteins to self-assembled monolayers presenting active site-directed capture ligands.
Proc Natl Acad Sci USA 99:5048-52

Houseman BT, Huh JH, Kron SJ, Mrkisch M (2002) Peptide chips for the quantitative evaluation of protein kinase activity Nature Biotechnol 20:270-274

Huang R, Lin Y, Wang CC, Gano J, Lin B, Shi Q, Boynton A, Burke J, Huang RP (2002) Connexin 43 suppresses human glioblastoma cell growth by down-regulation of monocyte chemotactic protein 1, as discovered using protein array technology
Cancer Res 62:2806-12

Hueber W, Utz PJ, Steinman L, Robinson WH (2002) Autoantibody profiling for the study and treatment of autoimmune disease. Arthritis Res. 4:290-5.

Kukar T, Eckenrode S, Gu Y, Lian W, Megginson M, She JX, Wu D (2002)
Protein microarrays to detect protein-protein interactions using red and green fluorescent proteins. Anal Biochem 306:50-4

Lee J, Bedford MT (2002) PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays. EMBO Rep 3:268-73

Lesaicherre ML, Lue RY, Chen GY, Zhu Q, Yao SQ (2002) Intein-mediated biotinylation of proteins and its application in a protein microarray.
J Am Chem Soc 124:8768-9

Lesaicherre ML, Uttamchandani M, Chen GY, Yao SQ (2002)
Antibody-Based fluorescence detection of kinase activity on a peptide array
Bioorg Med Chem Lett 12:2085-8

Li L, Chen S, Oh S, Jiang S (2002) In situ single-molecule detection of antibody-antigen binding by tapping-mode atomic force microscopy. Anal Chem 74:6017-22

Lin Y, Huang R, Santanam N, Liu YG, Parthasarathy S, Huang RP (2002) Profiling of human cytokines in healthy individuals with vitamin E supplementation by antibody array. Cancer Lett 187:17-24

Mezzasoma L, Bacarese-Hamilton T, Di Cristina M, Rossi R, Bistoni F, Crisanti A (2002) Antigen microarrays for serodiagnosis of infectious diseases
Clin Chem 48:121-30

Miller JC, Butler EB, Teh BS, Haab BB (2002) The application of protein microarrays to serum diagnostics: prostate cancer as a test case.
Dis Markers 17:225-34

Miyaji T, Hewitt SM, Liotta LA, Star RA. (2002) Frozen protein arrays: A new method for arraying and detecting recombinant and native tissue proteins.
Proteomics 2:1489-93

Morozov VN, Gavryushkin AV, Deev AA (2002) Direct detection of isotopically labeled metabolites bound to a protein microarray using a charge-coupled device
J Biochem Biophys Methods 51:57-67

Pawlak M, Schick E, Bopp MA, Schneider MJ, Oroszlan P, Ehrat M (2002) Zeptosens' protein microarrays: a novel high performance microarray platform for low abundance protein analysis. Proteomics 2:383-93

Reineke U, Ivascu C, Schlief M, Landgraf C, Gericke S, Zahn G, Herzel H, Volkmer-Engert R, Schneider-Mergener J (2002) Identification of distinct antibody epitopes and mimotopes from a peptide array of 5520 randomly generated sequences.
J Immunol Methods 267:37-51

Renault JP, Bernard A, Juncker D, Michel B, Bosshard HR, Delamarche E (2002) Fabricating microarrays of functional proteins using affinity contact printing.
Angew Chem Int Ed Engl 41:2320-3

Ringeisen BR, Wu PK, Kim H, Pique A, Auyeung RY, Young HD, Chrisey DB,
Krizman DB. (2002) Picoliter-scale protein microarrays by laser direct write.
Biotechnol Prog 18:1126-9

Robinson WH, DiGennaro C, Hueber W, Haab BB, Kamachi M, Dean EJ, Fournel S,
Fong D, Genovese MC, de Vegvar HE, Skriner K, Hirschberg DL, Morris RI, Muller S,
Pruijn GJ, van Venrooij WJ, Smolen JS, Brown PO, Steinman L, Utz PJ. (2002)
Autoantigen microarrays for multiplex characterization of autoantibody responses.
Nature Med 8:295-301

Robinson WH, Steinman L, Utz PJ (2002) Protein and peptide array analysis of autoimmune disease. Biotechniques Dec;Suppl:66-9

Sapsford KE, Charles PT, Patterson CH Jr, Ligler FS (2002) Demonstration of four immunoassay formats using the array biosensor. Anal Chem 74:1061-1068

Schaeferling M, Schiller S, Paul H, Kruschina M, Pavlickova P, Meerkamp M,
Giammasi C, Kambhampati D. (2002) Application of self-assembly techniques in the design of biocompatible protein microarray surfaces. Electrophoresis 23:3097-105

Schweitzer B, Roberts S, Grimwade B, Shao W, Wang M, Fu Q, Shu Q, Laroche I, Zhou Z, Tchernev VT, Christiansen J, Velleca M, Kingsmore SF (2002)
Multiplexed protein profiling on microarrays by rolling-circle amplification.
Nature Biotechnol 20:359-365

Schwenk JM, Stoll D, Templin MF, Joos TO (2002) Cell microarrays: an emerging technology for the characterization of antibodies. Biotechniques Dec;Suppl:54-61

Seong SY (2002) Microimmunoassay using a protein chip: optimizing conditions for protein immobilization. Clin Diagn Lab Immunol 9:927-30

Shieh J, To C, Carramao J, Nishimura N, Maruta Y, Hashimoto Y, Wright D, Wu HC, Azarani A (2002) High-throughput array production using precision glass syringes. Biotechniques 32:1360-2, 1364-5

Steinhauer C, Wingren C, Hager AC, Borrebaeck CA (2002) Single framework recombinant antibody fragments designed for protein chip applications.
Biotechniques Dec Suppl:38-45

Stich N, Gandhum A, Matyushin V, Raats J, Mayer C, Alguel Y, Schalkhammer T (2002) Phage Display Antibody-Based Proteomic Device Using Resonance-Enhanced Detection. J Nanosci Nanotechnol 2:375-381

Taitt CR, Anderson GP, Lingerfelt BM, Feldstein MJ, Ligler FS (2002) Nine-analyte detection using an array-based biosensor. Anal Chem. 74:6114-20.

Tam SW, Wiese R, Lee S, Gilmore J, Kumble KD (2002) Simultaneous analysis of eight human Th1/Th2 cytokines using microarrays. J Immunol Methods 261:157-65

Tantra R, Cooper J (2002) Imaging of protein arrays and gradients using softlithography and biochip technology.
Sensors and Actuators B: Chemical, 82: 233-240

Walton ID, Norton SM, Balasingham A, He L, Oviso DF Jr, Gupta D, Raju PA, Natan MJ, Freeman RG (2002). Particles for multiplexed analysis in solution: detection and identification of striped metallic particles using optical microscopy.
Anal Chem 74:2240-7

Wegner GJ, Lee HJ, Corn RM (2002) Characterization and optimization of peptide arrays for the study of epitope-antibody interactions using surface plasmon resonance imaging. Anal Chem 74:5161-8

Weng S. Gu K, Hammond PW, Lohse P, Rise C, Wagner RW, Wright MC, Kuimelis RG (2002) Generating addressable protein microarrays with PROfusionTM covalent mRNA-protein fusion technology. Proteomics 2:48-57

Woodbury RL, Varnum SM, Zangar RC (2002) Elevated HGF levels in sera from breast cancer patients detected using a protein microarray ELISA. J Proteome Res 1:233-7

Xu L, Aha P, Gu K, Kuimelis RG, Kurz M, Lam T, Lim AC, Liu H, Lohse PA, Sun L, Weng S, Wagner RW, Lipovsek D (2002) Directed evolution of high-affinity antibody mimics using mRNA display. Chem Biol 9:933-42

2001

Belov L, de la Vega O, dos Remedios CG, Mulligan SP, Christopherson RI (2001) Immunophenotyping of leukemias using a cluster of differentiation antibody microarray. Cancer Res 61:4483-9

Borrebaeck CA, Ekstrom S, Hager AC, Nilsson J, Laurell T, Marko-Varga G (2001)
Protein chips based on recombinant antibody fragments: a highly sensitive approach as detected by mass spectrometry. Biotechniques 30:1126-1132

Haab BB, Dunham MJ, Brown PO (2001) Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions.
Genome Biology 2:0004.1-0004.13

He M, Taussig MJ (2001) Single-step generation of protein arrays from DNA by cell free expression and in situ immobilisation (PISA method). Nucleic Acids Res 29: e73.

Huang RP (2001) Detection of multiple proteins in an antibody-based protein microarray system. J Immunol Methods 255:1-13

Huang RP, Huang R, Fan Y, Lin Y (2001) Simultaneous detection of multiple cytokines from conditioned media and patient's sera by an antibody-based protein array system. Anal Biochem 294:55-62

Karlström A, Nygren PA (2001) Dual labeling of a binding protein allows for specific fluorescence detection of native protein. Anal Biochem 295:22-30

Knezevic V, Leethanakul C, Bichsel VE, Worth JM, Prabhu VV, Gutkind JS, Liotta LA,
Munson PJ, Petricoin EF, Krizman DB (2001) Proteomic profiling of the cancer microenvironment by antibody arrays. Proteomics 1: 1271-1278

Lin SC, Tseng FG, Huang HM, Huang CY, Chieng CC (2001) Microsized 2D protein arrays immobilized by micro-stamps and micro-wells for disease diagnosis and drug screening. Fresenius J Anal Chem 371:202-8

Madoz-Gúrpide J, Wang H, Misek DE, Brichory F, Hanash SM (2001) Protein based microarrays: A tool for probing the proteome of cancer cells and tissues.
Proteomics 1: 1279-1287

Mayer C, Stich N, Palkovits R, Bauer G, Pittner F, Schalkhammer T. (2001) High-throughput assays on the chip based on metal nano-cluster resonance transducers. J. Pharm Biomed Anal 24:773-83

Mayer C, Stich N, Schalkhammer T, Bauer G (2001) Slide-format proteomic biochips based on surface-enhanced nanocluster-resonance.
Fresenius J Anal Chem 371:238-45

Moerman R, Frank J, Marijnissen JC, Schalkhammer TG, van Dedem GW. (2001) Miniaturized electrospraying as a technique for the production of microarrays of reproducible micrometer-sized protein spots. Anal Chem 73:2183-9

Nedelkov D, Nelson RW (2001) Analysis of human urine protein biomarkers via biomolecular interaction analysis mass spectrometry. Am J Kidney Dis 38:481-7

Nedelkov D, Nelson RW (2001) Delineation of in vivo assembled multiprotein complexes via biomolecular interaction analysis mass spectrometry.
Proteomics 1:1441-1446

Nicewarner-Pena SR, Freeman RG, Reiss BD, He L, Pena DJ, Walton ID, Cromer R, Keating CD, Natan MJ (2001) Submicrometer metallic barcodes.
Science 294:137-41

Sapsford KE, Liron Z, Shubin YS, Ligler FS (2001) Kinetics of antigen binding to arrays of antibodies in different sized spots. Anal Chem 73:5518-24

Sreekumar A, Nyati MK, Varambally S, Barrette TR, Ghosh D, Lawrence TS, Chinnaiyan AM (2001) Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins. Cancer Res 61:7585-93

Toepert F, Pires JR, Landgraf C, Oschkinat H, Schneider-Mergener J. (2001)
Synthesis of an Array Comprising 837 Variants of the hYAP WW Protein Domain.
Angew Chem Int Ed Engl 40:897-900

Zhu H, Bilgin M, Bangham R, Hall D, Casamayor A, Bertone P, Lan N, Jansen R, Bidlingmaier S, Houfek T, Mitchell T, Miller P, Dean RA, Gerstein M, Snyder M (2001)
Global analysis of protein activities using proteome chips. Science 293:2101-5

2000

Afanassiev V, Hanemann V, Wölfl S (2000) Preparation of DNA and protein micro arrays on glass slides coated with an agarose film. Nucleic Acids Res. 28:e66.

Arenkov P, Kukhtin A, Gemmell A, Voloshchuk S, Chupeeva V, Mirzabekov A (2000)
Protein microchips: use for immunoassay and enzymatic reactions.
Anal Biochem 278:123-131.

de Wildt RM, Mundy CR, Gorick BD, Tomlinson IM (2000) Antibody arrays for high-throughput screening of antibody-antigen interactions.
Nature Biotechnol 18:989-94

Emili AQ, Cagney G (2000) Large-scale functional analysis using peptide or protein arrays. Nature Biotechnol 18:393-397

Feng HP (2000) Picture story. A protein microarray. Nature Struct Biol 7:829

Ge H (2000) UPA, a universal protein array system for quantitative detection of protein-protein, protein-DNA, protein-RNA and protein-ligand interactions.
Nucleic Acids Res 28, e3

Holt LJ, Bussow K, Walter G, Tomlinson IM (2000) By-passing selection: direct screening for antibody-antigen interactions using protein arrays.
Nucleic Acids Res 28:e72.

Joos TO, Schrenk M, Hopfl P, Kroger K, Chowdhury U, Stoll D, Schorner D, Durr M,
Herick K, Rupp S, Sohn K, Hammerle H (2000) A microarray enzyme-linked immunosorbent assay for autoimmune diagnostics. Electrophoresis 21:2641-50

Luo LY, Diamandis EP (2000) Preliminary examination of time-resolved fluorometry for protein array applications. Luminescence 15:409-13.

MacBeath G, Schreiber SL (2000) Printing proteins as microarrays for high-throughput function determination. Science 289:1760-1763.

Nord K, Gunneriusson E, Uhlen M, Nygren PA (2000) Ligands selected from combinatorial libraries of protein A for use in affinity capture of apolipoprotein A-1M and taq DNA polymerase. J Biotechnol 80:45-54

Schweitzer B, Wiltshire S, Lambert J, O'Malley S, Kukanskis K, Zhu Z, Kingsmore SF, Lizardi PM, Ward DC (2000) Immunoassays with rolling circle DNA amplification: a versatile platform for ultrasensitive antigen detection.
Proc Natl Acad Sci USA 97:10113-9

Uetz P, Giot L, Cagney G, Mansfield TA, Judson RS, Knight JR, Lockshon D, Narayan V, Srinivasan M, Pochart P, Qureshi-Emili A, Li Y, Godwin B, Conover D, Kalbfleisch T, Vijayadamodar G, Yang M, Johnston M, Fields S, Rothberg JM. (2000)
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403:601-3

Zhu H, Klemic JF, Chang S, Bertone P, Casamayor A, Klemic KG, Smith D, Gerstein M, Reed MA, Snyder M (2000) Analysis of yeast protein kinases using protein chips.
Nature Genet 26:283-9

pre-2000

Bussow K, Cahill D, Nietfield W, Bancroft D, Scherzinger E, Lehrach H, Walter G (1998) A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library. Nucleic Acids Res 26:5007-5008

Guschin D, Yershov G, Zaslavsky A, Gemmell A, Shick V, Proudnikov D, Arenkov P, Mirzabekov A (1997) Manual manufacturing of oligonucleotide, DNA, and protein microchips. Anal Biochem 250:203-11

Jones VW, Kenseth JR, Porter MD, Mosher CL, Henderson E. (1998)
Microminiaturized immunoassays using atomic force microscopy and compositionally patterned antigen arrays. Anal Chem 70:1233-41

Lueking A, Horn M, Eickhoff H, Bussow K, Lehrach H, Walter G (1999) Protein Microarrays for Gene Expression and Antibody Screening.
Anal. Biochem. 270:103-111.

Mendoza LG, McQuary P, Mongan A, Gangadharan R, Brignac S, Eggers M (1999)
High-throughput microarray-based enzyme-linked immunosorbent assay (ELISA).
Biotechniques 27:778-788.

Mooney JF, Hunt AJ, McIntosh JR, Liberko CA, Walba DM, Rogers CT (1996)
Patterning of functional antibodies and other proteins by photolithography of silane monolayers. Proc Natl Acad Sci USA 93:12287-91

Rowe CA, Scruggs SB, Feldstein MJ, Golden JP, Ligler FS. (1999) An array immunosensor for simultaneous detection of clinical analytes.
Anal Chem 71:433-9.

Rowe CA, Tender LM, Feldstein MJ, Golden JP, Scruggs SB, MacCraith BD, Cras JJ, Ligler FS. (1999) Array biosensor for simultaneous identification of bacterial, viral, and protein analytes. Anal Chem 71:3846-52

Reviews

2004

Bodovitz S, Joos T (2004) The proteomics bottleneck: strategies for preliminary validation of potential biomarkers and drug targets. Trends Biotechnol. 22:4-7

Stoll D, Bachmann J, Templin MF, Joos TO (2004) Microarray technology: an increasing variety of screening tools for proteomic research. Targets 3:24-31

Tang N, Tornatore P, Weinberger SR. (2004) Current developments in SELDI affinity technology. Mass Spectrom Rev. 23:34-44

Zhang S (2004) Hydrogels: Wet or let die. Nature Materials 3:7-8

2003

Braun P, LaBaer J. (2003) High throughput protein production for functional proteomics. Trends Biotechnol. 21:383-8.

Cahill DJ, Nordhoff E (2003) Protein arrays and their role in proteomics. Adv Biochem Eng Biotechnol. 83:177-87.

Cutler P (2003) Protein arrays: The current state-of-the-art.
Proteomics 3:3-18

Fang Y, Lahiri J, Picard L (2003) G protein-coupled receptor microarrays for drug discovery. Drug Discov Today 8:755-61.

Forman JE, Suseno AD, Wagner P (2003) Surface and printing effects on fluorescent images of immobilized biomolecule arrays. Methods Enzymol. 361:530-48.

Gershon D (2003) Proteomics technologies: probing the proteome. Nature 424:581-7

Hanash S (2003) Disease proteomics. Nature 422:226-32

Howbrook DN, van der Valk AM, O'Shaughnessy MC, Sarker DK, Baker SC, Lloyd AW (2003) Developments in microarray technologies. Drug Discov Today 8:642-51

Huang RP (2003) Cytokine antibody arrays: a promising tool to identify molecular targets for drug discovery. Comb Chem High Throughput Screen. 6:769-75.

Jona G, Snyder M (2003) Recent developments in analytical and functional protein microarrays. Curr Opin Mol Ther 5:271-7

Kingsmore SF, Patel DD (2003) Multiplexed protein profiling on antibody-based microarrays by rolling circle amplification. Curr Opin Biotechnol 14:74-81

Kricka LJ, Joos T, Fortina P. (2003) Protein microarrays: a literature survey.
Clin Chem. 49:2109

Lopez MF, Pluskal MG (2003) Protein micro- and macroarrays: digitising the proteome. J Chromatogr B Analyt Technol Biomed Life Sci 787:19-27

Madoz-Gurpide J, Hanash SM (2003) Molecular analysis of cancer using DNA and protein microarrays. Adv Exp Med Biol. 532:51-8

Nedelkov D, Nelson RW (2003) Surface plasmon resonance mass spectrometry: recent progress and outlooks. Trends Biotechnol. 21:301-5.

Ng JH, Ilag LL (2003) Biochips beyond DNA: technologies and applications. Biotechnol Annu Rev. 9:1-149.

Phizicky E, Bastiaens PI, Zhu H, Snyder M, Fields S (2003) Protein analysis on a proteomic scale. Nature 422:208-15

Schweitzer B, Predki P, Snyder M. (2003) Microarrays to characterize protein interactions on a whole-proteome scale. Proteomics. 3:2190-9

Sercarz EE (2003) Arraying autoimmunity treatment. Nat Biotechnol. 21:1017-9

Taussig MJ, Landegren U (2003) Progress in antibody arrays. Targets 2:169-176

Templin MF, Stoll D, Schwenk JM, Potz O, Kramer S, Joos TO (2003) Protein microarrays: promising tools for proteomic research. Proteomics 3:2155-66

Tyers M, Mann M (2003) From genomics to proteomics. Nature 422:193-7.

Washburn MP (2003) Soft landing for protein chips. Nat Biotechnol. 21:1156-7

Wilson DS, Nock S (2003) Recent developments in protein microarray technology. Angew Chem Int Ed Engl 42:494-500

Wingren C, Ingvarsson J, Lindstedt M, Borrebaeck CA (2003) Recombinant antibody microarrays-a viable option? Nature Biotechnol 21:223

Wulfkuhle JD, Paweletz CP, Steeg PS, Petricoin EF 3rd, Liotta L (2003) Proteomic approaches to the diagnosis, treatment, and monitoring of cancer. Adv Exp Med Biol. 532:59-68.

Zhu H, Bilgin M, Snyder M (2003) Proteomics. Annu Rev Biochem. 72:783-812

Zhu H, Snyder M (2003) Protein chip technology. Curr Opin Chem Biol 7:55-63

2002

Abbott A (2002) Betting on tomorrow's chips. Nature 415:112-4

Bailey SN, Wu RZ, Sabatini DM (2002) Applications of transfected cell microarrays in high-throughput drug discovery. Drug Discovery Today 7:S113-S118

Beske OE, Goldbard S (2002) High-throughput cell analysis using multiplexed array technologies. Drug Discovery Today 7:S131-S135

Burbaum J, Tobal GM (2002) Proteomics in drug discovery.
Curr Opin Chem Biol 6:427-33

Charboneau L, Scott H, Chen T, Winters M, Petricoin III EF, Liotta LA, Paweletz CP (2002) Utility of reverse phase protein arrays: Applications to signalling pathways and human body arrays. Briefings Functional Genomics and Proteomics 1:305-315

Dower WJ, Mattheakis LC (2002) In vitro selection as a powerful tool for the applied evolution of proteins and peptides. Curr Opin Chem Biol 6:390-8

Eickhoff H, Konthur Z, Lueking A, Lehrach H, Walter G, Nordhoff E, Nyarsik L, Bussow K (2002) Protein array technology: the tool to bridge genomics and proteomics. Adv Biochem Eng Biotechnol 77:103-12

Elia G, Silacci M, Scheurer S, Scheuermann J, Neri D (2002) Affinity-capture reagents for protein arrays. Trends in Biotechnology 20:S19-S22 Suppl.

Figeys D (2002) Adapting arrays and lab-on-a-chip technology for proteomics. Proteomics 2:373-82

Frank R (2002) High-density synthetic Peptide microarrays: emerging tools for functional genomics and proteomics. Comb Chem High Throughput Screen 5:429-440

Frank R (2002) The SPOT-synthesis technique. Synthetic peptide arrays on membrane supports--principles and applications. J Immunol Methods 267:13-26

Gera JF, Hazbun TR, Fields S (2002) Array-based methods for identifying protein-protein and protein-nucleic acid interactions.
Methods Enzymol 350:499-512

Gilbert M, Albala JS (2002) Accelerating code to function: sizing up the protein production line. Curr Opin Chem Biol 6:102-5

Hallborn J, Carlsson R (2002) Automated screening procedure for high-throughput generation of antibody fragments. Biotechniques Dec; Suppl:30-7

Hardiman G (2002) Microarray Technologies - An Overview.
Pharmacogenomics 3:293

Houseman BT, Mrksich M (2002) Towards quantitative assays with peptide chips: a surface engineering approach. Trends Biotechnol 20:279-281

Huels C, Muellner S, Meyer HE, Cahill DJ (2002) The impact of protein biochips and microarrays on the drug development process. Drug Discovery Today 7:S119-124

Jain KK (2002) Post-genomic applications of lab-on-a-chip and microarrays.
Trends Biotechnol 20:184-5

James P (2002) Chips for proteomics: a new tool or just hype? Biotechniques Dec;Suppl:4-10

Joos TO, Stoll D, Templin MF (2002) Miniaturised multiplexed immunoassays.
Curr Opin Chem Biol 6:76-80

Kersten B, Burkle L, Kuhn EJ, Giavalisco P, Konthur Z, Lueking A, Walter G, Eickhoff H, Schneider U (2002) Large-scale plant proteomics.